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\(\frac{2^{19}.27^3+15.4^9.9^4}{6^9.2^{10}+12^{10}}\)
\(=\frac{2^{19}.\left(3^3\right)^3+3.5.\left(2^2\right)^9.\left(3^2\right)^4}{\left(2.3\right)^9.2^{10}+\left(2^2.3\right)^{10}}\)
\(=\frac{2^{19}.3^9+3.5.2^{18}.3^8}{2^9.3^9.2^{10}+2^{20}.3^{10}}\)
\(=\frac{2^{19}.3^9+2^{19}.3^9.5}{2^{19}.3^9+2^{20}.3^{10}}\)
\(=\frac{2^{19}.3^9.\left(1+5\right)}{2^{19}.3^9\left(1+2.3\right)}\)
\(=\frac{6}{7}\)
\(\frac{2^8\times6}{3^3\times5^4}\div\frac{8^3\times9}{5^3\times3^3}-\left(2^{14}+3^{19}\right)\left(3^{81}+5^{64}\right)\left(2^4-4^2\right)\)
\(=\frac{2^9\times3}{3^3\times5^4}\times\frac{5^3\times3^3}{2^9\times3^2}-\left(2^{14}+3^{19}\right)\left(3^{81}+5^{64}\right)\left(2^4-2^4\right)\)
\(=\frac{2^9\times3^4\times5^3}{3^5\times5^4\times2^9}-\left(2^{14}+3^{19}\right)\left(3^{81}+5^{64}\right)\times0\)
\(=\frac{1}{3\times5}-0\)
\(=\frac{1}{15}\)